metyrapone

Term ID

CHEBI:44241

Synonyms

• 2-methyl-1,2-dipyridin-3-ylpropan-1-one
• metirapona
• Metopiron
• Metopirone
• METYRAPONE
• metyraponum

Definition

An aromatic ketone that is 3,3-dimethylbutan-2-one in which the methyl groups at positions 1 and 4 are replaced by pyridin-3-yl groups. A steroid 11beta-monooxygenase (EC 1.14.15.4) inhibitor, it is used in the diagnosis of adrenal insufficiency.

References

• Beilstein:163023
• CAS:54-36-4
• DrugBank:DB01011
• Drug_Central:1791
• KEGG:C07205
• KEGG:D00410
• LINCS:LSM-3035
• PDBeChem:MYT
• Patent:US2966493
• Reaxys:163023
• Wikipedia:Metyrapone

Ontology

ChEBI  ( EBI )

Resources

CTD