Search Ontology:
ChEBI

obeticholic acid

Term ID
CHEBI:43602
Synonyms
  • (3alpha,5beta,6alpha,7alpha)-6-ethyl-3,7-dihydroxycholan-24-oic acid
  • 6-ECDCA
  • 6-Ethyl-CDCA
  • 6-Ethylchenodeoxycholic acid
  • 6alpha-ethyl-3alpha,7alpha-dihydroxy-5beta-cholan-24-oic acid
  • 6alpha-Ethyl-chenodeoxycholic acid
  • 6alpha-ethylchenodeoxycholic acid
  • INT 747
  • INT-747
  • INT747
  • obeticholic acid
  • Ocaliva
Definition
A dihydroxy-5beta-cholanic acid that is chenodeoxycholic acid carrying an additional ethyl substituent at the 6alpha-position. A semi-synthetic bile acid which acts as a farnesoid X receptor agonist and is used for treatment of primary biliary cholangitis.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_functional_parent
has_role
Phenotype
Phenotype resulting from obeticholic acid
Phenotype where environments contain obeticholic acid
Phenotype modified by environments containing obeticholic acid
Human Disease / Model Data
Citations
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