ertapenem

Term ID

CHEBI:404903

Synonyms

(1R,5S,6S,8R,2'S,4'S)-2-(2-(3-carboxyphenylcarbamoyl)pyrrolidin-4-ylthio)-6-(1-hydroxyethyl)-1-methylcarbapenem-3-carboxylic acid
(4R,5S,6S)-3-((3S,5S)-5-((3-carboxyphenyl)carbamoyl)pyrrolidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-aza-bicyclo[3.2.0]hept-2-ene-2-carboxylic acid
(4R,5S,6S)-3-({(3S,5S)-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl}sulfanyl)-6-[(1R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
ERTAPENEM

Definition

Meropenem in which the one of the two methyl groups attached to the amide nitrogen is replaced by hydrogen while the other is replaced by a 3-carboxyphenyl group. The sodium salt is used for the treatment of moderate to severe susceptible infections including intra-abdominal and acute gynaecological infections, pneumonia, and infections of the skin and of the urinary tract.

References

Beilstein:9025520
CAS:153832-46-3
DrugBank:DB00303
Drug_Central:1046
KEGG:D07908
Patent:US5478820
Patent:WO9315078
Wikipedia:Ertapenem

Ontology

ChEBI ( EBI )

Relationships

is a type of: carbapenemcarboxylic acid pyrrolidinecarboxamide

carbapenemcarboxylic acid pyrrolidinecarboxamide Show first 5 Terms
has_role: antibacterial drug

antibacterial drug Show first 5 Terms
inverse is_conjugate_base_of: ertapenem(1-)

ertapenem(1-) Show first 5 Terms
is_conjugate_acid_of: ertapenem(1-)

ertapenem(1-) Show first 5 Terms

Phenotype

Phenotype resulting from ertapenem

Phenotype where environments contain ertapenem

Phenotype modified by environments containing ertapenem

Human Disease / Model Data

Citations