compactin diol lactone

Term ID

CHEBI:34652

Synonyms

(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}oxan-2-one
(4R,6R)-4-hydroxy-6-{2-[(1S,2S,8S,8aR)-8-hydroxy-2-methyl-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]ethyl}tetrahydro-2H-pyran-2-one
Antibiotic ML 236A
compactin diol lactone
desmethylmonacolin J
ML 236A
ML-236A

Definition

A carbobicyclic compound that is ML-236C substituted by a hydroxy group at position 8S. It is a fungal metabolite isolated from Penicillium citrinum and exhibits anticholesteremic activity.

References

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 2-pyranones carbobicyclic compound hexahydronaphthalenes polyketide secondary alcohol

2-pyranones carbobicyclic compound hexahydronaphthalenes polyketide secondary alcohol Show first 5 Terms
has_functional_parent: ML-236C

ML-236C Show first 5 Terms
has_role: antiatherosclerotic agent anticholesteremic drug antilipemic drug antimicrobial agent EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor ... Show All 6 Terms

antiatherosclerotic agent anticholesteremic drug antilipemic drug antimicrobial agent EC 1.1.1.34/EC 1.1.1.88 (hydroxymethylglutaryl-CoA reductase) inhibitor fungal metabolite Show first 5 Terms

Phenotype

Phenotype resulting from compactin diol lactone

Phenotype where environments contain compactin diol lactone

Phenotype modified by environments containing compactin diol lactone

Human Disease / Model Data

Citations