nicorandil

Term ID

CHEBI:31905

Synonyms

• 2-[(pyridin-3-ylcarbonyl)amino]ethyl nitrate
• 2-nicotinamidoethyl nitrate
• Adancor
• Ikorel
• N-(2-hydroxyethyl)nicotinamide nitrate
• nicorandil
• nicorandilum
• Perisalol
• SG 75
• SG-75
• Sigmart

Definition

A pyrimidinecarboxamide that is nicotinamide in which one of the hydrogens attached to the carboxamide nitrogen is replaced by a 2-(nitrooxy)ethyl group. It has both nitrate-like and ATP-sensitive potassium channel activator properties, and is used for the prevention and treatment of angina pectoris.

References

• cas:65141-46-0
• drugcentral:1919
• kegg.compound:C13280
• kegg.drug:D01810
• lincs.smallmolecule:LSM-6009
• patent:DE2714713
• patent:US4200640
• pubmed:23841868
• pubmed:23845070
• pubmed:24685703
• pubmed:24837014
• pubmed:24952900
• pubmed:25319832
• wikipedia.en:Nicorandil

Ontology

ChEBI  ( EBI )