gemcitabine hydrochloride

Term ID

CHEBI:31647

Synonyms

2',2'-Difluorodeoxycytidine monohydrochloride
2'-deoxy-2',2'-difluorocytidine hydrochloride
2'-Deoxy-2',2'-difluorocytidine monohydrochloride
Gemcitabine HCl

Definition

A 2'-deoxycytidine hydrochloriode having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine hydrochloride is used in the treatment of various carcinomas, including non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer.

References

Beilstein:5386970
CAS:122111-03-9
DrugBank:DB00441
KEGG:D01155

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrochloride organofluorine compound

hydrochloride organofluorine compound Show first 5 Terms
has_part: gemcitabine

gemcitabine Show first 5 Terms
has_role: anticoronaviral agent antimetabolite antineoplastic agent antiviral drug EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor ... Show All 7 Terms

anticoronaviral agent antimetabolite antineoplastic agent antiviral drug EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor immunosuppressive agent radiosensitizing agent Show first 5 Terms

Phenotype

Phenotype resulting from gemcitabine hydrochloride

Phenotype where environments contain gemcitabine hydrochloride

Phenotype modified by environments containing gemcitabine hydrochloride

Human Disease / Model Data

Citations