Search Ontology:
ChEBI

epothilone B

Term ID
CHEBI:31550
Synonyms
  • (-)-epothilone B
  • (1S,3S,7S,10R,11S,12S,16R)-7,11-dihydroxy-8,8,10,12,16-pentamethyl-3-[(1E)-1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-4,17-dioxabicyclo[14.1.0]heptadecane-5,9-dione
  • EPO 906
  • Epo B
  • EpoB
  • epothilone B
  • patupilona
  • patupilone
  • patupilonum
Definition
An epithilone that is epithilone D in which the double bond in the macrocyclic ring has been oxidised to the corresponding epoxide (the S,S stereoisomer).
References
  • cas:152044-54-7
  • drugbank:DB03010
  • kegg.compound:C12154
  • knapsack:C00044747
  • lipidmaps:LMPK04000041
  • pdb-ccd:EPB
  • pubmed:10831849
  • pubmed:21743064
  • pubmed:22234539
  • pubmed:22688083
  • pubmed:22918719
  • pubmed:23205945
  • pubmed:23214997
  • pubmed:23801302
  • pubmed:24374386
  • pubmed:24470546
  • pubmed:24583341
  • pubmed:24913659
  • pubmed:25694444
  • pubmed:25721485
  • pubmed:25765066
  • pubmed:25919223
  • pubmed:26081685
  • pubmed:26308485
  • pubmed:26316786
  • reaxys:7556514
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from epothilone B
Phenotype where environments contain epothilone B
Phenotype modified by environments containing epothilone B
Phenotype affecting epothilone B
Human Disease Model