cyclothiazide

Term ID

CHEBI:31448

Synonyms

• 3-(bicyclo[2.2.1]hept-5-en-2-yl)-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-3,4-dihydro-3-(2-norbornen-5-yl)-7-sulfamoyl-1,2,4-benzothiadiazine 1,1-dioxide
• 6-chloro-3,4-dihydro-3-(5-norbornen-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
• 6-chloro-3-(2-norbornen-5-yl)-7-sulfamyl-3,4-dihydro-1,2,4-benzothiadiazine 1,1-dioxide
• ciclotiazida
• cyclothiazide
• cyclothiazidum

Definition

3,4-Dihydro-2H-1,2,4-benzothiadiazine 1,1-dioxide substituted at positions 3, 5 and 6 by a 2-norbornen-5-yl group, chlorine, and a sulfonamide group, respectively. A thiazide diuretic, it has been used in the management of hypertension and oedema.

References

• Beilstein:722843
• CAS:2259-96-3
• DrugBank:DB00606
• Drug_Central:761
• KEGG:C12685
• KEGG:D01256
• LINCS:LSM-4421
• PDBeChem:CYZ
• PMID:19338354
• Patent:US3275625
• Wikipedia:Cyclothiazide

Ontology

ChEBI  ( EBI )

Resources

CTD