Search Ontology:
ChEBI

crotamiton

Term ID
CHEBI:31439
Synonyms
  • crotalgin
  • crotamiton
  • crotamitone
  • crotamitonum
  • crotonyl-N-ethyl-o-toluidine
  • N-ethyl-N-(2-methylphenyl)but-2-enamide
  • N-ethyl-o-crotonotoluidide
Definition
An enamide resulting from the formal condensation of crotonic acid with N-ethyl-2-methylaniline. A colourless or pale yellow oily liquid, it is used in the treatment of pruritus (itching) by producing a counter-irritation: as it evaporates from the skin, it produces a cooling effect that diverts attention away from the itching. It has also been used as an acaricide in the treatment of scabies, though more effective drugs are usually preferred.
References
  • beilstein:3275497
  • cas:483-63-6
  • drugbank:DB00265
  • drugcentral:744
  • kegg.drug:D01381
  • lincs.smallmolecule:LSM-3274
  • patent:GB615137
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
Phenotype
Phenotype resulting from crotamiton
Phenotype where environments contain crotamiton
Phenotype modified by environments containing crotamiton
Phenotype affecting crotamiton
Human Disease Model