AZ505

Term ID

CHEBI:228259

Synonyms

AZ 505
AZ-505
N-cyclohexyl-3-[2-(3,4-dichlorophenyl)ethylamino]-N-[2-[2-(5-hydroxy-3-oxo-4H-1,4-benzoxazin-8-yl)ethylamino]ethyl]propanamide
N-cyclohexyl-N(3)-[2-(3,4-dichlorophenyl)ethyl]-N-(2-{[2-(5-hydroxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-8-yl)ethyl]amino}ethyl)-beta-alaninamide

Definition

A benzoxazine that is 2H-1,4-benzoxazin-3(4H)-one substituted by a hydroxy group at position 5 and a 2-{[2-(cyclohexyl{N-[2-(3,4-dichlorophenyl)ethyl]-beta-alanyl}amino)ethyl]amino}ethyl group at position 8. It is a potent and selective inhibitor of SMYD2.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzoxazine dichlorobenzene organic hydroxy compound secondary amino compound tertiary carboxamide

benzoxazine dichlorobenzene organic hydroxy compound secondary amino compound tertiary carboxamide Show first 5 Terms
has_role: antineoplastic agent EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor

antineoplastic agent EC 2.1.1.354 ([histone H3]-lysine(4) N-trimethyltransferase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from AZ505

Phenotype where environments contain AZ505

Phenotype modified by environments containing AZ505

Human Disease / Model Data

Citations