clobetasol

Term ID

CHEBI:205919

Synonyms

(11beta,16beta)-21-chloro-9-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione
21-chloro-9-fluoro-11beta,17-dihydroxy-16beta-methylpregna-1,4-diene-3,20-dione
clobetasol
clobetasolum

Definition

A 3-oxo-Delta(1),Delta(4)-steroid that is 16beta-methylpregna-1,4-diene-3,20-dione bearing hydroxy groups at the 11beta and 17alpha positions, fluorine at position 9, and a chlorine substituent at position 21. It is used as its 17alpha-propionate ester to treat various skin disorders, including exzema and psoriasis.

References

Beilstein:6748271
CAS:25122-41-2
DrugBank:DB01013
KEGG:D07715
PMID:26658258
PMID:27012570
Patent:DE1902340
Patent:US3721687

Ontology

ChEBI ( EBI )

Resources

CTD

Relationships

is a type of: 3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid chlorinated steroid ... Show All 8 Terms

3-oxo-Delta(1),Delta(4)-steroid 11beta-hydroxy steroid 17alpha-hydroxy steroid 20-oxo steroid chlorinated steroid fluorinated steroid glucocorticoid tertiary alpha-hydroxy ketone Show first 5 Terms
has_role: anti-inflammatory drug SMO receptor agonist

anti-inflammatory drug SMO receptor agonist Show first 5 Terms
inverse has_functional_parent: clobetasol propionate

clobetasol propionate Show first 5 Terms

Phenotype

Phenotype resulting from clobetasol

Phenotype where environments contain clobetasol

Phenotype modified by environments containing clobetasol

Human Disease / Model Data

Citations