leucettine L41

Term ID

CHEBI:195521

Synonyms

(5Z)-2-anilino-5-(1,3-benzodioxol-5-ylmethylidene)-3,5-dihydro-4H-imidazol-4-one

Definition

A member of the class of benzodioxoles that is 1,3-benzodioxole substituted by a (2-anilino-5-oxo-1,5-dihydro-4H-imidazol-4-ylidene)methyl group at position 5. It is an inhibitor of DYRK1A, DYRK2, CLK1, and CLK3 (IC50s = 0.04, 0.035, 0.015, and 4.5 muM, respectively).

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: benzodioxoles imidazolone substituted aniline

benzodioxoles imidazolone substituted aniline Show first 5 Terms
has_role: autophagy inducer EC 2.7.11.22 (cyclin-dependent kinase) inhibitor EC 2.7.12.1 (dual-specificity kinase) inhibitor neuroprotective agent nootropic agent

autophagy inducer EC 2.7.11.22 (cyclin-dependent kinase) inhibitor EC 2.7.12.1 (dual-specificity kinase) inhibitor neuroprotective agent nootropic agent Show first 5 Terms

Phenotype

Phenotype resulting from leucettine L41

Phenotype where environments contain leucettine L41

Phenotype modified by environments containing leucettine L41

Human Disease / Model Data

Citations