Search Ontology:
ChEBI
INDY
- Term ID
- CHEBI:195332
- Synonyms
-
- (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2(3H)-ylidene)propan-2-one
- (1Z)-1-(3-ethyl-5-hydroxy-1,3-benzothiazol-2-ylidene)propan-2-one
- (1Z)-1-(3-ethyl-5-hydroxy-2(3H)-benzothiazolylidene)-2-propanone
- Definition
- A member of the class of benzothiazoles that is 2,3-dihydro-1,3-benzothiazole substituted by 2-oxopropylidene, ethyl, and hydroxy groups at positions 2, 3 and 5, respectively. It is an ATP-competitive inhibitor of Dyrk1A and Dyrk1B (IC50 of 0.24 μM and 0.23 μM, respectively).
- References
-
- cas:1169755-45-6
- pdb-ccd:EHB
- pubmed:20981014
- pubmed:23635774
- pubmed:24188002
- pubmed:26048785
- pubmed:29985601
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from INDY
Phenotype where environments contain INDY
Phenotype modified by environments containing INDY
Phenotype affecting INDY
Human Disease Model