Search Ontology:
ChEBI
cefaloram
- Term ID
- CHEBI:192380
- Synonyms
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- (6R,7R)-3-[(acetyloxy)methyl]-8-oxo-7-(2-phenylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
- 3-(Acetoxymethyl)-8-oxo-7-(phenylacetamido)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid
- cefaloram
- cefaloramo
- cefaloramum
- cephaloram
- Definition
- A cephalosporin derivative with potent antibacterial activity which binds to and inactivates penicillin-binding proteins (PBPs) located on the inner membrane of the bacterial cell wall. PBPs are enzymes involved in the terminal stages of assembling the bacterial cell wall and in reshaping the cell wall during growth and division, inactivation of which interferes with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity, resulting in the weakening of the bacterial cell wall and causing cell lysis.
- References
- Ontology
- ChEBI ( EBI )
- is a type of
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- has_role
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Show first 5 Terms
Phenotype
Phenotype resulting from cefaloram
Phenotype where environments contain cefaloram
Phenotype modified by environments containing cefaloram
Human Disease / Model Data
Citations