Search Ontology:
ChEBI

3beta-(2-diethylaminoethoxy)androst-5-en-17-one

Term ID
CHEBI:190402
Synonyms
  • 3beta-(2-(diethylamino)ethoxy)androst-5-en-17-one
  • 3beta-[2-(diethylamino)ethoxy]androst-5-en-17-one
  • U-18666A (free base)
  • U18666A (free base)
Definition
A 17-oxo steroid that is dehydroepiandrosterone in which the hydroxy group at position 3β is replaced by a 2-(diethylamino)ethoxy group. It is a cholesterol biosynthesis inhibitor and induces cataracts in rats.
References
  • cas:2855-62-1
  • chemspider:8129693
  • pdb-ccd:MKM
  • pubmed:11171067
  • pubmed:15102959
  • pubmed:15322907
  • pubmed:16033255
  • pubmed:16149744
  • pubmed:179297
  • pubmed:19158313
  • pubmed:31165728
  • pubmed:467524
  • pubmed:6661410
  • pubmed:9514411
Ontology
ChEBI  ( EBI )
Relationships
Phenotype
Phenotype resulting from 3beta-(2-diethylaminoethoxy)androst-5-en-17-one
Phenotype where environments contain 3beta-(2-diethylaminoethoxy)androst-5-en-17-one
Phenotype modified by environments containing 3beta-(2-diethylaminoethoxy)androst-5-en-17-one
Phenotype affecting 3beta-(2-diethylaminoethoxy)androst-5-en-17-one
Human Disease Model