L-744,832

Term ID

CHEBI:183636

Synonyms

L 744,832
L 744832
L-744832
L744832
propan-2-yl (2S)-2-(2-{[(2S,3S)-2-{[(2R)-2-amino-3-sulfanylpropyl]amino}-3-methylpentyl]oxy}-3-phenylpropanamido)-4-(methylsulfonyl)butanoate

Definition

A secondary carboxamide resulting from the formal condensation of the carboxy group of 2-{[(2S,3S)-2-{[(2R)-2-amino-3-sulfanylpropyl]amino}-3-methylpentyl]oxy}-3-phenylpropanoic acid with the amino group of propan-2-yl (2S)-2-amino-4-(methylsulfonyl)butanoate. It is a farnesyltransferase inhibitor that exhibits anticancer properties.

References

cas:160141-09-3
chemspider:4953632
lincs.smallmolecule:LSM-36916
pubmed:10498620
pubmed:10602510
pubmed:10667233
pubmed:10753872
pubmed:10825141
pubmed:10912583
pubmed:10935512
pubmed:12420225
pubmed:12479217
pubmed:15069557
pubmed:15958645
pubmed:16224182
pubmed:18022825
pubmed:18489761
pubmed:18509318
pubmed:18930822
pubmed:22361350
pubmed:22737247
pubmed:22843692
pubmed:29719594
pubmed:7585182
pubmed:9418856
pubmed:9918200

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from L-744,832

Phenotype where environments contain L-744,832

Phenotype modified by environments containing L-744,832

Phenotype affecting L-744,832

Human Disease Model