Search Ontology:
ChEBI
cortisol
- Term ID
- CHEBI:17650
- Synonyms
-
- (11beta)-11,17,21-trihydroxypregn-4-ene-3,20-dione
- 11beta,17,21-trihydroxypregn-4-ene-3,20-dione
- 11beta,17alpha,21-trihydroxy-4-pregnene-3,20-dione
- 11beta-hydrocortisone
- 17-hydroxycorticosterone
- 4-pregnen-11beta,17alpha,21-triol-3,20-dione
- cortisol
- hidrocortisona
- Hydrocortisone
- hydrocortisonum
- Kendall's compound F
- Reichstein's substance M
- Definition
- A 17alpha-hydroxy-C21-steroid that is pregn-4-ene substituted by oxo groups at positions 3 and 20 and hydroxy groups at positions 11, 17 and 21. Cortisol is a corticosteroid hormone or glucocorticoid produced by zona fasciculata of the adrenal cortex, which is a part of the adrenal gland. It is usually referred to as the "stress hormone" as it is involved in response to stress and anxiety, controlled by corticotropin-releasing hormone (CRH). It increases blood pressure and blood sugar, and reduces immune responses.
- References
-
- Beilstein:1354819
- CAS:50-23-7
- DrugBank:DB00741
- Drug_Central:1388
- KEGG:C00735
- KEGG:D00088
- LINCS:LSM-5980
- LIPID_MAPS_instance:LMST02030001
- PDBeChem:HCY
- PMID:10438974
- PMID:2268561
- Patent:US2602769
- Wikipedia:Hydrocortisone
- Ontology
- ChEBI ( EBI )
- Resources
- CTD
- is a type of
- has_parent_hydride
-
- has_role
- inverse has_functional_parent
Show All 8 Terms
Show first 5 Terms
Phenotype
Phenotype resulting from cortisol
Phenotype where environments contain cortisol
Phenotype modified by environments containing cortisol
Human Disease / Model Data
Citations