komodoquinone A

Term ID

CHEBI:167003

Synonyms

(+)-komodoquinone A
(8S,10S)-6,8,10,11-tetrahydroxy-8-methyl-5,12-dioxo-5,7,8,9,10,12-hexahydrotetracen-1-yl 3,6-dideoxy-3-(dimethylamino)-alpha-L-galactopyranoside

Definition

An anthracycline that is komodoquinone B in which the hydroxy group at position 1 is replaced by a 3,6-dideoxy-3-(dimethylamino)-α-L-galactopyranoside group. First isolated from the marine bacterium Streptomyces sp. KS3, it induces neuronal cell differentiation in the neuroblastoma cell line.

References

cas:630094-57-4
knapsack:C00031956
patent:JP2005080616
pubmed:14575440
pubmed:14646317
pubmed:30995392

Ontology

ChEBI ( EBI )

Relationships

Phenotype

Phenotype resulting from komodoquinone A

Phenotype where environments contain komodoquinone A

Phenotype modified by environments containing komodoquinone A

Phenotype affecting komodoquinone A

Human Disease Model