taltirelin tetrahydrate

Term ID

CHEBI:157598

Synonyms

(-)-N-[(S)-hexahydro-1-methyl- 2,6-dioxo-4-pyrimidinyl-carbonyl]-L-histidyl-L-prolinamide tetrahydrate
Ceredist
N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide tetrahydrate
N-{[(4S)-1-methyl-2,6-dioxohexahydropyrimidin-4-yl]carbonyl}-L-histidyl-L-prolinamide--water (1/4)

Definition

A hydrate that is the tetrahydrate form of taltirelin. It activates neuronal cells by promoting the release and turnover of neurotransmitters (acetylcholine, dopamine) and its nerve growth factor-like action. The drug is approved in Japan and used to treat ataxia (daily activities such as gait, eating, and conversation) in patients suffering from spinocerebellar degeneration.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: hydrate

hydrate Show first 5 Terms
has_part: taltirelin

taltirelin Show first 5 Terms
has_role: central nervous system drug

central nervous system drug Show first 5 Terms

Phenotype

Phenotype resulting from taltirelin tetrahydrate

Phenotype where environments contain taltirelin tetrahydrate

Phenotype modified by environments containing taltirelin tetrahydrate

Human Disease / Model Data

Citations