6-de(cyclopropylamino)-6-(isobutylamino)abacavir

Term ID

CHEBI:149437

Synonyms

• (1S,4R)-4-[2-amino-6-[(2-methylpropyl)amino]-9H-purin-9-yl]-2-cyclopentene-1-methanol
• [(1S,4R)-4-{2-amino-6-[(2-methylpropyl)amino]-9H-purin-9-yl}cyclopent-2-en-1-yl]methanol
• {(1S,4R)-4-[2-amino-6-(isobutylamino)-9H-purin-9-yl]cyclopent-2-en-1-yl}methanol

Definition

A 2,6-diaminopurine that is an analogue of abacavir in which the cyclopropylamino group at position 6 of the purine moiety is replaced by an isobutylamino group. One of a series of synthesised abacavir analogues with antiviral activity found to stimulate IFN-gamma secretion in abacavir-responsive clones.

References

• PMID:31549414

Ontology

ChEBI  ( EBI )