marinobufagenin

Term ID

CHEBI:146151

Synonyms

(3beta,5beta,14alpha,15beta)-3,5-dihydroxy-14,15-epoxybufa-20,22-dienolide
3beta,5-dihydroxy-5beta,15beta-14,15-epoxybufa-20,22-dienolide
Marinobufagin
MBG

Definition

A cardiotonic steroid secreted by the toad Bufo rubescens and other related species such as Bufo marinus. An endogenous Na/K-ATPase inhibitor, it is a vasoconstrictor with effects similar to digitalis.

References

Ontology

ChEBI ( EBI )

Relationships

is a type of: epoxy steroid steroid hormone

epoxy steroid steroid hormone Show first 5 Terms
has_functional_parent: (5beta)-bufadienolide

(5beta)-bufadienolide Show first 5 Terms
has_role: EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor epitope

EC 3.6.3.9 (Na(+)/K(+)-transporting ATPase) inhibitor epitope Show first 5 Terms

Phenotype

Phenotype resulting from marinobufagenin

Phenotype where environments contain marinobufagenin

Phenotype modified by environments containing marinobufagenin

Human Disease / Model Data

Citations