dihydroartemisinic acid

Term ID

CHEBI:144078

Synonyms

• (-)-dihydroartemisinic acid
• (2R)-2-[(1R)-4beta,7-Dimethyl-1,2,3,4,4abeta,5,6,8abeta-octahydronaphthalen-1alpha-yl]propionic acid
• (2R)-2-[(1R,4R,4aS,8aS)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl]propanoic acid
• dihydroarteannuic acid
• dihydroartemisinic acid

Definition

A monocarboxylic acid that is propanoic acid substituted at position 2 by a (1S,4R,4aS,8aR)-4,7-dimethyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl group. It is a sesquiterpenoid precursor of the antimalarial drug, artemisinin.

References

• cas:85031-59-0
• knapsack:C00030130
• metacyc.compound:CPD-7559
• pubmed:17295513
• pubmed:20050663
• pubmed:22247290
• pubmed:28566563
• pubmed:28846664
• pubmed:29311435
• pubmed:30154807

Ontology

ChEBI  ( EBI )