Search Ontology:
ChEBI

ravuconazole

Term ID
CHEBI:143825
Synonyms
  • 4-[2-[(2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1,2,4-triazol-1-yl)butan-2-yl]-1,3-thiazol-4-yl]benzonitrile
  • BMS 207147
  • BMS-20714
  • ER 30346
  • ER-30346
  • ravuconazol
  • ravuconazole
  • ravuconazolum
Definition
A member of the class of triazoles that is 1-butyl-1H-1,2,4-triazole in which the butyl group is substituted at positions 2, 2, and 3 by hydroxy, 2,4-difluorophenyl, and 4-(p-cyanophenyl)-1,3-thiazol-2-yl groups, respectively (the R,R stereoisomer). It exhibits antifungal activity by inhibition of 14alpha demethylase, an enzyme involved in sterol synthesis, resulting in lysis of the fungal cell wall and fungal cell death. (NCIO4)
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from ravuconazole
Phenotype where environments contain ravuconazole
Phenotype modified by environments containing ravuconazole
Human Disease / Model Data
Citations
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