4-(2,6-difluorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Term ID

CHEBI:143124

Synonyms

4-(2,6-difluorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide
4-([(2,6-difluorophenyl)carbonyl]amino)-N-piperidin-4-yl-1H-pyrazole-3-carboxamide
4-[(2,6-difluorophenyl)carbonylamino]-N-piperidin-4-yl-1H-pyrazole-3-carboxamide
UNC-YL-206

Definition

A member of the class of pryrazoles that is 4-amino-1H-pyrazole-3-carboxylic acid in which the primary amino group has been acylated by a 2,6-difluorobenzoyl group and in which the carboxylic acid has been converted to a carboxamide by formal condensation with the primary amino group of 4-aminopiperidine. It is a CDK1, CDK2 and CDK17 kinase inhibitor.

References

PDBeChem:LZA
PMID:18656911

Ontology

ChEBI ( EBI )

Relationships

is a type of: difluorobenzene piperidines pyrazoles secondary carboxamide

difluorobenzene piperidines pyrazoles secondary carboxamide Show first 5 Terms
has_role: EC 2.7.11.22 (cyclin-dependent kinase) inhibitor

EC 2.7.11.22 (cyclin-dependent kinase) inhibitor Show first 5 Terms

Phenotype

Phenotype resulting from 4-(2,6-difluorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Phenotype where environments contain 4-(2,6-difluorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Phenotype modified by environments containing 4-(2,6-difluorobenzamido)-N-(piperidin-4-yl)-1H-pyrazole-3-carboxamide

Human Disease / Model Data

Citations