CMB4563

Term ID

CHEBI:142445

Synonyms

• 1-(4-(1H-pyrrol-1-yl)phenyl)-3-methyl-8-(pyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
• 3-methyl-8-(pyridin-3-yl)-1-[4-(1H-pyrrol-1-yl)phenyl]-1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one
• CMB 4563
• CMB-4563

Definition

An imidazoquinoline that is 1,3-dihydro-2H-imidazo[4,5-c]quinolin-2-one which is substituted at positions 1, 3, and 8 by by p-(pyrrol-1-yl)phenyl, methyl, and pyridin-3-yl group, respectively. A potent and specific inhibitor of Target Of Rapamycin Complex 2 (TORC2).

References

• PMID:28976958
• PMID:29895620
• Reaxys:33175572

Ontology

ChEBI  ( EBI )