vibegron

Term ID

CHEBI:142418

Synonyms

• (6S)-N-[4-({(2S,5R)-5-[(R)-hydroxy(phenyl)methyl]pyrrolidin-2-yl}methyl)phenyl]-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxamide
• Beova
• MK-4618
• vibegron
• vibegronum

Definition

A pyrrolopyrimidine obtained by formal condensation of the carboxy group of (6S)-4-oxo-4,6,7,8-tetrahydropyrrolo[1,2-a]pyrimidine-6-carboxylic acid with the amino group of (R)-[(2R,5S)-5-(4-aminobenzyl)pyrrolidin-2-yl](phenyl)methanol. It is a β3-adrenergic receptor agonist currently in clinical development for the treatment of patients with overactive bladder.

References

• cas:1190389-15-1
• kegg.drug:D10433
• pubmed:26709102
• pubmed:27965369
• pubmed:29366513
• pubmed:29752752
• reaxys:19541234

Ontology

ChEBI  ( EBI )