trisodium phosphonoformate

Term ID

CHEBI:141644

Synonyms

foscarnet sodique
foscarnet sodium
foscarneto sodico
foscarnetum natricum
trisodium carboxyphosphate
trisodium carboxyphosphate (anhydrous)
trisodium dioxidophosphinecarboxylate oxide
trisodium phosphonoformate
trisodium phosphonoformate (anhydrous)

Definition

The trisodium salt of phosphonoformic acid. It is used as an antiviral agent in the treatment of cytomegalovirus retinitis (CMV retinitis, an inflamation of the retina that can lead to blindness) and as an alternative to ganciclovir for AIDS patients who require concurrent antiretroviral therapy but are unable to tolerate ganciclovir due to haematological toxicity.

References

CAS:63585-09-1
DrugBank:DB00529
KEGG:D00579

Ontology

ChEBI ( EBI )

Relationships

is a type of: one-carbon compound organic sodium salt

one-carbon compound organic sodium salt Show first 5 Terms
has_part: phosphonatoformate

phosphonatoformate Show first 5 Terms
has_role: antiviral drug

antiviral drug Show first 5 Terms
inverse has_part: trisodium phosphonoformate hexahydrate

trisodium phosphonoformate hexahydrate Show first 5 Terms

Phenotype

Phenotype resulting from trisodium phosphonoformate

Phenotype where environments contain trisodium phosphonoformate

Phenotype modified by environments containing trisodium phosphonoformate

Human Disease / Model Data

Citations