spiraprilat

Term ID

CHEBI:141522

Synonyms

• (8S)-7-((S)-N-((S)-1-Carboxy-3-phenylpropyl)alanyl)-1,4-dithia-7-azaspiro(4.4)nonane-8-carboxylic acid
• (8S)-7-[(2S)-2-{[(1S)-1-carboxy-3-phenylpropyl]amino}propanoyl]-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid
• 7-[N-(1(S)-carboxy-3-phenylpropyl)-S-alanyl]-1,4-dithia-7-azaspiro[4.4]nonane-8(S)-carboxylic acid
• Spiraprilate
• Spiraprilatum

Definition

An azaspiro compound that is spirapril in which the ethyl ester group has been hydrolysed to the corresponding carboxylic acid group. It is the active metabolite of the angiotensin-converting enzyme (ACE) inhibitor spirapril.

References

• cas:83602-05-5
• kegg.drug:D03775
• pubmed:1384174
• pubmed:7505361
• pubmed:8061850
• pubmed:9269955
• reaxys:4275869
• wikipedia.en:Spiraprilat

Ontology

ChEBI  ( EBI )

Resources

CTD