Search Ontology:
ChEBI

16,16-dimethylprostaglandin E2

Term ID
CHEBI:141046
Synonyms
  • (5Z,11alpha,13E,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-5,13-dien-1-oic acid
  • 16,16-dimethyl Prostaglandin E2
  • 16,16-Dimethyl-pge2
  • 16,16-Dimethyl-prostaglandin E2
  • 9-oxo-11R,15R-dihydroxy-16,16-dimethyl-5Z,13E-prostadienoic acid
  • dmPGE(2)
  • dmPGE2
Definition
A prostanoid that is prostaglandin E2 in which both of the hydrogens at position 16 have been replaced by methyl groups. A synthetic analogue of prostaglandin E2, it is a potent inhibitor of pancreatic function and growth of experimental tumors. It also protects the gastric mucosa, prevents ulceration, and promotes the healing of peptic ulcers.
References
Ontology
ChEBI  ( EBI )
Resources
CTD
Relationships
is a type of
has_role
Phenotype
Phenotype resulting from 16,16-dimethylprostaglandin E2
Phenotype where environments contain 16,16-dimethylprostaglandin E2
Phenotype modified by environments containing 16,16-dimethylprostaglandin E2
Human Disease / Model Data
Citations
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