cisatracurium

Term ID

CHEBI:140621

Synonyms

• (1R,2R,1'R,2'R)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]
• (1R,2R,1'R,2'R)-atracurium
• (1R-cis,1'R-cis)-2,2'-{pentane-1,5-diylbis[oxy(3-oxopropane-3,1-diyl)]}bis[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolinium]
• (1R-cis,1'R-cis)-atracurium

Definition

A diester that is the (1R,1'R,2R,2'R)-diastereoisomer of atracurium, a quaternary ammonium ion consisting of pentane-1,5-diol with both hydroxy functions bearing 3-[1-(3,4-dimethoxybenzyl)-6,7-dimethoxy-2-methyl-3,4-dihydroisoquinolinium-2(1H)-yl]propanoyl groups. The active species in the skeletal muscle relaxant cisatracurium besylate.

References

• cas:96946-41-7
• drugbank:DB00565
• patent:WO2013189800
• pubmed:27703625
• pubmed:28239805
• pubmed:28351905
• pubmed:28367286
• pubmed:28770545
• pubmed:29324189
• pubmed:29368335
• pubmed:29517695
• pubmed:29635320
• reaxys:8184048

Ontology

ChEBI  ( EBI )