Search Ontology:
ChEBI
prinomastat
- Term ID
- CHEBI:138885
- Synonyms
-
- (3S)-N-hydroxy-2,2-dimethyl-4-{[4-(pyridin-4-yloxy)phenyl]sulfonyl}thiomorpholine-3-carboxamide
- (S)-2,2-dimethyl-4-{[p-(4-pyridyloxy)phenyl]sulfonyl}-3-thiomorpholinecarbohydroxamic acid
- AG 3340
- AG-3340
- AG3340
- prinomastat
- prinomastatum
- Definition
- A hydroxamic acid that is (3S)-N-hydroxy-2,2-dimethylthiomorpholine-3-carboxamide in which the hydrogen attached to the thiomorpholine nitrogen has been replaced by a [4-(pyridin-4-yloxy)phenyl]sulfonyl group. It is a selective inhibitor with of matrix metalloproteinases (MMPs) 2, 3, 9, 13, and 14.
- References
-
- cas:192329-42-3
- drugbank:DB05100
- kegg.drug:D03797
- patent:US5753653
- patent:WO9720824
- pdb-ccd:PN0
- pubmed:10980656
- pubmed:11114600
- pubmed:11436949
- pubmed:11726397
- pubmed:12187478
- pubmed:12187492
- pubmed:14871966
- pubmed:15279727
- pubmed:15492635
- pubmed:15681529
- pubmed:16103944
- pubmed:16502351
- pubmed:22308038
- pubmed:23403478
- wikipedia.en:Prinomastat
- Ontology
- ChEBI ( EBI )
Phenotype
Phenotype resulting from prinomastat
Phenotype where environments contain prinomastat
Phenotype modified by environments containing prinomastat
Phenotype affecting prinomastat
Human Disease Model