lifitegrast

Term ID

CHEBI:133023

Synonyms

• lifitegrast
• N-[2-(1-benzofuran-6-carbonyl)-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carbonyl]-3-(methanesulfonyl)-L-phenylalanine
• SAR 1118
• SAR-1118
• SAR1118
• Xiidra

Definition

An N-acyl-L-α-amino acid obtained by formal condensation of the carboxy group of N-[2-(1-benzofuran-6-carbonyl)]-5,7-dichloro-1,2,3,4-tetrahydroisoquinoline-6-carboxylic acid with the amino group of 3-(methanesulfonyl)-L-phenylalanine. Used for treatment of keratoconjunctivitis sicca (dry eye syndrome).

References

• cas:1025967-78-5
• drugcentral:5174
• kegg.drug:D10374
• pubmed:20334535
• pubmed:20445119
• pubmed:21330663
• pubmed:22330307
• pubmed:22538219
• pubmed:23215542
• pubmed:23256487
• pubmed:24289915
• pubmed:24900456
• pubmed:26365210
• pubmed:26807723
• pubmed:27055211
• pubmed:27354762
• pubmed:27388660
• reaxys:19179816
• wikipedia.en:Lifitegrast

Ontology

ChEBI  ( EBI )