dacomitinib

Term ID

CHEBI:132268

Synonyms

• (2E)-N-[4-(3-chloro-4-fluoroanilino)-7-methoxyquinazolin-6-yl]-4-(piperidin-1-yl)but-2-enamide
• dacomitinib
• dacomitinibum
• PF 00299804-03
• PF-00299804
• PF-00299804-03

Definition

A member of the class of quinazolines that is 7-methoxyquinazoline-4,6-diamine in which the amino group at position 4 is substituted by a 3-chloro-4-fluorophenyl group and the amino group at position 6 is substituted by an (E)-4-(piperidin-1-yl)but-2-enoyl group.

References

• cas:1110813-31-4
• kegg.drug:D09883
• pdb-ccd:1C9
• pubmed:22753918
• pubmed:22761403
• pubmed:24853121
• pubmed:25669172
• pubmed:26179237
• pubmed:26768165
• pubmed:26792360
• pubmed:26899759
• pubmed:27070370
• pubmed:27289242
• reaxys:12400147
• wikipedia.en:Dacomitinib

Ontology

ChEBI  ( EBI )