cefalotin

Term ID

CHEBI:124991

Synonyms

• (6R,7R)-3-(acetoxymethyl)-8-oxo-7-(thiophen-2-ylacetamido)-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid
• 3-Acetoxymethyl-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid
• 7-(2'-thienylacetamido)cephalosporanic acid
• 7-(2-Thienylacetamido)cephalosporanic acid
• 7-(Thiophene-2-acetamido)cephalosporin
• 7beta-(thiophen-2-ylacetamido)-3-acetoxymethyl-3,4-didehydrocepham-4-carboxylic acid
• Cefalothin
• Cefalotin
• cefalotina
• cefalotine
• cefalotinum
• Cephalothin
• Cephalotin
• CET

Definition

A semisynthetic, first-generation cephalosporin antibiotic with acetoxymethyl and (2-thienylacetyl)nitrilo moieties at positions 3 and 7, respectively, of the core structure. Administered parenterally during surgery and to treat a wide spectrum of blood infections.

References

• Beilstein:945586
• CAS:153-61-7
• DrugBank:DB00456
• Drug_Central:574
• HMDB:HMDB0014599
• KEGG:C07761
• KEGG:D07635
• LINCS:LSM-15184
• PDBeChem:CLS
• PMID:10930630
• PMID:12569987
• PMID:12833570
• PMID:1384868
• PMID:13963283
• PMID:1701026
• PMID:2083978
• PMID:23472927
• PMID:23680238
• PMID:29017833
• PMID:6176550
• Patent:FR1384197
• Patent:US3218318
• Reaxys:945586
• Wikipedia:Cephalothin

Ontology

ChEBI  ( EBI )

Resources

CTD