Search Ontology:
ChEBI

zileuton

Term ID
CHEBI:10112
Synonyms
  • (+-)-1-(1-Benzo[b]thien-2-ylethyl)-1-hydroxyurea
  • 1-[1-(1-benzothien-2-yl)ethyl]-1-hydroxyurea
  • Leutrol
  • N-(1-Benzo(b)thien-2-ylethyl)-N-hydroxyurea
  • N-[1-(benzo[b]thiophen-2-yl)ethyl]-N-hydroxyurea
  • Zileuton
  • zileutonum
  • Zyflo
Definition
A member of the class of 1-benzothiophenes that is 1-benzothiophene in which the hydrogen at position 2 is replaced by a 1-[carbamoyl(hydroxy)amino]ethyl group. A selective 5-lipoxygenase inhibitor, it inhibits the formation of leukotrienes LTB4, LTC4, LDT4, and LTE4. It is used for the management of chronic asthma.
References
Ontology
ChEBI  ( EBI )
Relationships
is a type of
has_parent_hydride
has_role
Phenotype
Phenotype resulting from zileuton
Phenotype where environments contain zileuton
Phenotype modified by environments containing zileuton
Human Disease / Model Data
Citations
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