OBO ID: GO:0060070
Term Name: canonical Wnt signaling pathway Search Ontology:
Synonyms:
  • canonical Wnt receptor signaling pathway
  • canonical Wnt-activated signaling pathway
  • frizzled-1 receptor signaling pathway
  • Wnt receptor signaling pathway through beta-catenin
  • Wnt receptor signaling pathway via beta-catenin
  • Wnt receptor signalling pathway through beta-catenin
Definition: A type of Wnt signaling pathway in which Wnt binding to its receptor on the surface of a target cell results in the by propagation of the molecular signals via beta-catenin, and end with a change in transcription of target genes. In this pathway, the activated receptor signals via downstream effectors that result in the inhibition of beta-catenin phosphorylation, thereby preventing degradation of beta-catenin. Stabilized beta-catenin can then accumulate and travel to the nucleus to trigger changes in transcription of target genes. (2)
References:
Ontology: GO: Biological Process    QuickGO    AmiGO
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