ZFIN Human Disease: autoimmune lymphoproliferative syndrome

OBO ID: DOID:6688

Term Name:	autoimmune lymphoproliferative syndrome		Search Ontology:
Synonyms:	ALPS Canale-Smith syndrome
Definition:	A hypersensitivity reaction type IV disease that is an inherited disorder in which the body cannot properly regulate the number of immune system cells (lymphocytes). It is characterized by the production of an abnormally large number of lymphocytes. Accumulation of excess lymphocytes results in enlargement of the lymph nodes, the liver, and the spleen. http://ghr.nlm.nih.gov/condition/autoimmune-lymphoproliferative-syndrome
References:	GARD:8686 ICD10CM:D89.82 ICD9CM:279.41 MESH:D056735 NCI:C37864 OMIM:601859 ORDO:3261 SNOMEDCT_US_2023_03_01:702444009 UMLS_CUI:C1328840
Ontology:	Human Disease ( DOID:6688 )

Relationships

is a type of:	hypersensitivity reaction type IV disease hypersensitivity reaction type IV disease Show first 5 Terms
has subtype:	autoimmune lymphoproliferative syndrome type 2A autoimmune lymphoproliferative syndrome type 2B autoimmune lymphoproliferative syndrome type 3 autoimmune lymphoproliferative syndrome type 4 autoimmune lymphoproliferative syndrome type 2A autoimmune lymphoproliferative syndrome type 2B autoimmune lymphoproliferative syndrome type 3 autoimmune lymphoproliferative syndrome type 4 Show first 5 Terms

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Alliance (1)

GENES INVOLVED

Human Gene	Zebrafish Ortholog	OMIM Term	OMIM Phenotype ID
FAS	fas	Autoimmune lymphoproliferative syndrome, type IA	601859
		{Autoimmune lymphoproliferative syndrome}	601859
FASLG	faslg	Autoimmune lymphoproliferative syndrome, type IB	601859

ZEBRAFISH MODELS No data available

PHENOTYPE No data available

CITATIONS: None