OBO ID: DOID:0060775
Term Name: microvillus inclusion disease Search Ontology:
Synonyms:
  • congenital familial protracted diarrhea with enterocyte brush-border abnormalities
  • congenital microvillus atrophy
  • Davidson disease
  • diarrhea 2 with microvillus atrophy
  • intractable diarrhea of infancy
  • MVD
Definition: A congenital diarrhea characterized by onset of intractable life-threatening watery diarrhea during infancy, lack of microvilli on the surface of enterocytes and occurrence of intracellular vacuolar structures containing microvilli that has_material_basis_in homozygous or compound heterozygous mutation in the MYO5B gene on chromosome 18q21. https://www.ncbi.nlm.nih.gov/pubmed/18724368
References:
Ontology: Human Disease   (DOID:0060775)
OTHER microvillus inclusion disease PAGES
GENES INVOLVED
Human Gene Zebrafish Ortholog OMIM Term OMIM Phenotype ID
MYO5B Diarrhea 2, with microvillus atrophy, with or without cholestasis 251850
ZEBRAFISH MODELS
Fish Conditions Citations
myo5bt30834/t30834 standard conditions Sidhaye et al., 2016
PHENOTYPE No data available

CITATIONS (2)