OBO ID: CHEBI:92511
Term Name: ketotifen Search Ontology:
Synonyms:
  • 10-(1-methyl-4-piperidinylidene)-5H-benzo[1,2]cyclohepta[3,4-b]thiophen-4-one
  • 4-(1-methylpiperidin-4-ylidene)-4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one
  • ketotifen
  • ketotifene
  • ketotifeno
  • ketotifenum
Definition: An organic heterotricyclic compound that is 4,9-dihydro-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one which is substituted at position 4 by a 1-methylpiperidin-4-ylidene group. A blocker of histamine H1 receptors with a stabilising action on mast cells, it is used (usually as its hydrogen fumarate salt) for the treatment of asthma, where it may take several weeks to exert its full effect.
References:
  • CAS:34580-13-7
  • DrugBank:DB00920
  • Drug_Central:1530
  • HMDB:HMDB0015056
  • KEGG:D08105
  • LINCS:LSM-2637
  • Patent:DE2111071
  • Patent:US3682930
  • Wikipedia:Ketotifen
Ontology: ChEBI  ( EBI )
PHENOTYPE No data available