ZFIN ChEBI: donepezil

OBO ID: CHEBI:53289

Term Name:	donepezil		Search Ontology:
Synonyms:	2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindan-1-one donepezil donepezilo donepezilum
Definition:	A racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine.
References:	Beilstein:7081955 CAS:120014-06-4 DrugBank:DB00843 Drug_Central:946 KEGG:D07869 LINCS:LSM-1598 Reaxys:7081955 Wikipedia:Donepezil
Ontology:	ChEBI ( EBI )

Relationships

is a type of:	racemate racemate Show first 5 Terms
has_part:	(R)-donepezil (S)-donepezil (R)-donepezil (S)-donepezil Show first 5 Terms
has_role:	EC 3.1.1.7 (acetylcholinesterase) inhibitor EC 3.1.1.8 (cholinesterase) inhibitor nootropic agent EC 3.1.1.7 (acetylcholinesterase) inhibitor EC 3.1.1.8 (cholinesterase) inhibitor nootropic agent Show first 5 Terms
inverse is_conjugate_acid_of:	donepezil (1+) donepezil (1+) Show first 5 Terms
is_conjugate_base_of:	donepezil (1+) donepezil (1+) Show first 5 Terms

PHENOTYPE No data available