Term: hematopoietic multipotent progenitor cell negative regulation of canonical Wnt signaling pathway
Note: This page represents a term created by the combination ("post-composition") of two ontology terms. For more information on the individual terms, click the hyperlinked name.
Name: hematopoietic multipotent progenitor cell
Synonyms: hemopoietic progenitor cell
Definition: A hematopoietic multipotent progenitor cell is multipotent, but not capable of long-term self-renewal. These cells are characterized as lacking lineage cell surface markers and being CD34-positive in both mice and humans.
Ontology: Anatomy Ontology [ZFA:0009354]
Name: negative regulation of canonical Wnt signaling pathway
Synonyms: negative regulation of canonical Wnt receptor signaling pathway, negative regulation of canonical Wnt receptor signalling pathway, negative regulation of canonical Wnt-activated signaling pathway, negative regulation of catenin import into nucleus, negative regulation of catenin protein nuclear translocation, negative regulation of Wnt receptor signaling pathway through beta-catenin
Definition: Any process that decreases the rate, frequency, or extent of the Wnt signaling pathway through beta-catenin, the series of molecular signals initiated by binding of a Wnt protein to a frizzled family receptor on the surface of the target cell, followed by propagation of the signal via beta-catenin, and ending with a change in transcription of target genes.
Ontology: GO: Biological Process [GO:0090090]    QuickGO    AmiGO