ZFIN is now using GRCz12tu for Genomic Data
Gene
capn15
- ID
- ZDB-GENE-140106-70
- Name
- calpain 15
- Symbol
- capn15 Nomenclature History
- Previous Names
-
- zmp:0000001110 (1)
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in disease of mental health. Orthologous to human CAPN15 (calpain 15).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Ma et al., 2019
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Oculogastrointestinal neurodevelopmental syndrome | 619318 |
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR000169 | Cysteine peptidase, cysteine active site |
| Domain | IPR001300 | Peptidase C2, calpain, catalytic domain |
| Domain | IPR001876 | Zinc finger, RanBP2-type |
| Family | IPR022684 | Peptidase C2, calpain family |
| Homologous_superfamily | IPR036443 | Zinc finger, RanBP2-type superfamily |
| Homologous_superfamily | IPR038765 | Papain-like cysteine peptidase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Cysteine peptidase, cysteine active site | Papain-like cysteine peptidase superfamily | Peptidase C2, calpain, catalytic domain | Peptidase C2, calpain family | Zinc finger, RanBP2-type | Zinc finger, RanBP2-type superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:E7FAX5 | InterPro | 1122 | ||||||
| UniProtKB:A0A8M2BLF5 | InterPro | 1153 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
capn15-201
(1)
|
Ensembl | 3,369 nt | ||
| mRNA |
capn15-202
(1)
|
Ensembl | 3,462 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance