ZFIN is now using GRCz12tu for Genomic Data
Gene
slc25a1b
- ID
- ZDB-GENE-130114-1
- Name
- slc25a1 solute carrier family 25 member 1b
- Symbol
- slc25a1b Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 10 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable citrate:succinate antiporter activity. Involved in neuromuscular junction development. Predicted to be located in mitochondrial inner membrane. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in 2-hydroxyglutaric aciduria; combined D-2- and L-2-hydroxyglutaric aciduria; and congenital myasthenic syndrome. Orthologous to human SLC25A1 (solute carrier family 25 member 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chaouch et al., 2014
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| combined D-2- and L-2-hydroxyglutaric aciduria | Alliance | Combined D-2- and L-2-hydroxyglutaric aciduria | 615182 |
| Myasthenic syndrome, congenital, 23, presynaptic | 618197 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Mitochondrial carrier protein | Mitochondrial carrier protein domain superfamily | Mitochondrial carrier protein, transmembrane region | Tricarboxylate transport protein-like |
|---|---|---|---|---|---|---|
| UniProtKB:F1R4U0 | InterPro | 317 | ||||
| UniProtKB:A0AC58GKN5 | InterPro | 317 | ||||
| UniProtKB:A0AC58GKQ9 | InterPro | 365 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc25a1b-201
(1)
|
Ensembl | 2,242 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers