npc1l1

ID

ZDB-GENE-110510-5

Name

NPC1-like 1

Symbol

npc1l1 Nomenclature History

Previous Names

None

Type

protein_coding_gene

Location

Chr: 8 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable lipid carrier activity. Predicted to be involved in cholesterol transport. Predicted to be located in endomembrane system and membrane. Is expressed in intestine and liver. Orthologous to human NPC1L1 (NPC1 like intracellular cholesterol transporter 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With npc1l1 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		[Ezetimibe, nonresponse to]	617966
		[Low density lipoprotein cholesterol level QTL 7]	617966

Associated With npc1l1 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

No data available

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9QJ16	InterPro	1411
UniProtKB:A0AC58GBG7	InterPro	1392
UniProtKB:A0AC58GBG8	InterPro	1358
UniProtKB:A0AC58GBH8	InterPro	1358
UniProtKB:A0AC58GBI8	InterPro	1392
UniProtKB:A0AC58GBJ6	InterPro	1358