ZFIN is now using GRCz12tu for Genomic Data
Gene
ikzf2
- ID
- ZDB-GENE-100922-169
- Name
- IKAROS family zinc finger 2
- Symbol
- ikzf2 Nomenclature History
- Previous Names
-
- si:zfos-1425h8.1 (1)
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Unknown
- Description
- Predicted to enable DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in telencephalon. Human ortholog(s) of this gene implicated in immune system disease. Orthologous to human IKZF2 (IKAROS family zinc finger 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| ICHAD syndrome | Alliance | Immunodysregulation, craniofacial anomalies, hearing impairment, athelia, and developmental delay | 621234 |
| immunodysregulation with variable immunodeficiency and autoimmunity | Alliance | Immunodysregulation with variable immunodeficiency and autoimmunity | 621233 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | Ikaros C2H2-type zinc-finger | Zinc finger C2H2 superfamily | Zinc finger C2H2-type |
|---|---|---|---|---|---|
| UniProtKB:A0A0R4IIC7 | InterPro | 499 | |||
| UniProtKB:C4XVB5 | InterPro | 495 | |||
| UniProtKB:A0AC58GCW3 | InterPro | 526 | |||
| UniProtKB:A0AC58GCW6 | InterPro | 518 | |||
| UniProtKB:A0AC58GCW8 | InterPro | 514 | |||
| UniProtKB:A0AC58GCX1 | InterPro | 518 | |||
| UniProtKB:A0AC58GCX2 | InterPro | 518 | |||
| UniProtKB:A0AC58GCX3 | InterPro | 518 | |||
| UniProtKB:A0AC58GCX5 | InterPro | 526 | |||
| UniProtKB:A0AC58GCX6 | InterPro | 526 | |||
| UniProtKB:A0AC58GCX7 | InterPro | 499 | |||
| UniProtKB:A0AC58GCX8 | InterPro | 499 | |||
| UniProtKB:A0AC58GCY2 | InterPro | 514 | |||
| UniProtKB:A0AC58GCY3 | InterPro | 473 | |||
| UniProtKB:A0AC58GCY4 | InterPro | 518 | |||
| UniProtKB:A0AC58GCY5 | InterPro | 522 | |||
| UniProtKB:A0AC58GCY6 | InterPro | 477 | |||
| UniProtKB:A0AC58GCY8 | InterPro | 477 | |||
| UniProtKB:A0AC58GCY9 | InterPro | 495 | |||
| UniProtKB:A0AC58GCZ0 | InterPro | 499 | |||
| UniProtKB:A0AC58GCZ1 | InterPro | 477 | |||
| UniProtKB:A0AC58GCZ5 | InterPro | 495 | |||
| UniProtKB:A0AC58GCZ7 | InterPro | 526 | |||
| UniProtKB:A0AC58GCZ8 | InterPro | 473 | |||
| UniProtKB:A0AC58GD02 | InterPro | 495 | |||
| UniProtKB:A0AC58GD10 | InterPro | 499 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers
- Comparative Orthology
- Alliance