ZFIN is now using GRCz12tu for Genomic Data
Gene
nhlrc2
- ID
- ZDB-GENE-100318-2
- Name
- NHL repeat containing 2
- Symbol
- nhlrc2 Nomenclature History
- Previous Names
- None
- Type
- protein_coding_gene
- Location
- Chr: 12 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to be involved in cell redox homeostasis. Predicted to be located in cytosol. Human ortholog(s) of this gene implicated in neurodegenerative disease. Orthologous to human NHLRC2 (NHL repeat containing 2).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- No data available
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Uusimaa et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| FINCA syndrome | 618278 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Additional Resources | Length | NHL2, NHL repeat domain | NHL repeat | Six-bladed beta-propeller, TolB-like | Thioredoxin domain | Thioredoxin-like fold | Thioredoxin-like superfamily |
|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M3BE96 | InterPro | 719 | ||||||
| UniProtKB:A0AC58GY69 | InterPro | 382 | ||||||
| UniProtKB:A0A8M9QN08 | InterPro | 719 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
nhlrc2-201
(1)
|
Ensembl | 5,008 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers