ZFIN is now using GRCz12tu for Genomic Data
Gene
caspbl
- ID
- ZDB-GENE-090311-53
- Name
- caspase b, like
- Symbol
- caspbl Nomenclature History
- Previous Names
-
- casp19b (1)
- si:ch211-15j1.6
- Type
- protein_coding_gene
- Location
- Chr: 1 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Predicted to enable cysteine-type endopeptidase activity. Predicted to be involved in several processes, including positive regulation of inflammatory response; positive regulation of neuron apoptotic process; and pyroptotic inflammatory response. Predicted to be part of NLRP1 inflammasome complex. Predicted to be active in cytosol. Orthologous to human CASP4 (caspase 4).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR016129 | Peptidase family C14A, His active site |
| Active_site | IPR033139 | Peptidase family C14A, cysteine active site |
| Domain | IPR001309 | Peptidase C14, p20 domain |
| Domain | IPR002138 | Peptidase C14, caspase non-catalytic subunit p10 |
| Domain | IPR004020 | DAPIN domain |
| Domain | IPR011600 | Peptidase C14, caspase domain |
| Domain | IPR015917 | Peptidase C14A, caspase catalytic domain |
| Family | IPR002398 | Peptidase C14 family |
| Homologous_superfamily | IPR011029 | Death-like domain superfamily |
| Homologous_superfamily | IPR029030 | Caspase-like domain superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | Caspase-like domain superfamily | DAPIN domain | Death-like domain superfamily | Peptidase C14A, caspase catalytic domain | Peptidase C14, caspase domain | Peptidase C14, caspase non-catalytic subunit p10 | Peptidase C14 family | Peptidase C14, p20 domain | Peptidase family C14A, cysteine active site | Peptidase family C14A, His active site |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A2U9DQQ6 | InterPro | 395 | ||||||||||
| UniProtKB:B8A526 | InterPro | 409 | ||||||||||
| UniProtKB:A0AC58JCA0 | InterPro | 430 | ||||||||||
| UniProtKB:A0AC58JCA1 | InterPro | 395 | ||||||||||
| UniProtKB:A0AC58JCB7 | InterPro | 395 | ||||||||||
| UniProtKB:A0AC58JCC1 | InterPro | 395 |
- Genome Browsers
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
caspbl-201
(1)
|
Ensembl | 1,230 nt | ||
| mRNA |
caspbl-202
(1)
|
Ensembl | 1,993 nt |
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers