ZFIN is now using GRCz12tu for Genomic Data
Gene

nsun6

ID
ZDB-GENE-080808-8
Name
NOP2/Sun RNA methyltransferase 6
Symbol
nsun6 Nomenclature History
Previous Names
None
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Genome Assembly
GRCz12tu
Annotation Status
Current
Description
Predicted to enable rRNA (cytosine-C5-)-methyltransferase activity. Predicted to be involved in rRNA base methylation. Human ortholog(s) of this gene implicated in autosomal recessive intellectual developmental disorder 82. Orthologous to human NSUN6 (NOP2/Sun RNA methyltransferase 6).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nsun6 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive intellectual developmental disorder 82 Alliance Intellectual developmental disorder, autosomal recessive 82 620779
Associated With nsun6 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018314 RsmB/NOL1/NOP2-like, conserved site
Domain IPR001678 SAM-dependent methyltransferase RsmB-F/NOP2-type domain
Domain IPR049560 SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core
Family IPR023267 RNA (C5-cytosine) methyltransferase
Homologous_superfamily IPR015947 PUA-like superfamily
Homologous_superfamily IPR029063 S-adenosyl-L-methionine-dependent methyltransferase superfamily
Homologous_superfamily IPR036974 PUA domain superfamily
Domain Details Per Protein
Protein Additional Resources Length PUA domain superfamily PUA-like superfamily RNA (C5-cytosine) methyltransferase RsmB/NOL1/NOP2-like, conserved site S-adenosyl-L-methionine-dependent methyltransferase superfamily SAM-dependent methyltransferase RsmB-F/NOP2-type, catalytic core SAM-dependent methyltransferase RsmB-F/NOP2-type domain
UniProtKB:A0A0R4IAT4 InterPro 459
UniProtKB:A0A8M6Z0B3 InterPro 458
UniProtKB:A0AC58G1T3 InterPro 459
UniProtKB:A0AC58G1T5 InterPro 459
UniProtKB:A0AC58G1T6 InterPro 458
UniProtKB:A0AC58G1U1 InterPro 459
UniProtKB:A0AC58G1U8 InterPro 339
UniProtKB:A0AC58G1V0 InterPro 339
UniProtKB:A0AC58G1V2 InterPro 339
UniProtKB:A0AC58G1V4 InterPro 458
UniProtKB:A0AC58G1V8 InterPro 339
UniProtKB:A0AC58G1V9 InterPro 458
UniProtKB:A0AC58G1W0 InterPro 339
UniProtKB:A0AC58G1W2 InterPro 458
UniProtKB:A0AC58G1X2 InterPro 459
UniProtKB:A0AC58G1X5 InterPro 458
UniProtKB:A0AC58G214 InterPro 458
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA nsun6-201 (1)
Ensembl
Ensembl 1,702 nt
ZFIN BLAST
mRNA nsun6-202 (1)
Ensembl
Ensembl 1,603 nt
ZFIN BLAST
mRNA nsun6-203 (1)
Ensembl
Ensembl 1,796 nt
ZFIN BLAST
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Genome Browsers
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations
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