abcb6b

ID

ZDB-GENE-070912-584

Name

ATP binding cassette subfamily B member 6 (LAN blood group) b

Symbol

abcb6b Nomenclature History

Previous Names

si:dkey-7j20.1

Type

protein_coding_gene

Location

Chr: 9 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable ABC-type heme transporter activity; ATP binding activity; and ATP hydrolysis activity. Predicted to be involved in heme transmembrane transport. Predicted to be located in several cellular components, including bounding membrane of organelle; endoplasmic reticulum membrane; and extracellular region. Human ortholog(s) of this gene implicated in dyschromatosis universalis hereditaria. Orthologous to human ABCB6 (ATP binding cassette subfamily B member 6 (LAN blood group)).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

No data available

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

No data available

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With abcb6b Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
dyschromatosis universalis hereditaria	Alliance	Dyschromatosis universalis hereditaria 3	615402
		Microphthalmia/coloboma 7	614497
		Pseudohyperkalemia, familial, 2, due to red cell leak	609153
		[Blood group, Langereis system]	111600

Associated With abcb6b Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017871	ABC transporter-like, conserved site
Domain	IPR003439	ABC transporter-like, ATP-binding domain
Domain	IPR003593	AAA+ ATPase domain
Domain	IPR011527	ABC transporter type 1, transmembrane domain
Family	IPR039421	Type 1 protein exporter
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036640	ABC transporter type 1, transmembrane domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9Q4W6	InterPro	683
UniProtKB:A0A8M2BF06	InterPro	648
UniProtKB:A0A8M9QB69	InterPro	422
UniProtKB:A0AC58GFY9	InterPro	422
UniProtKB:A0AC58GFZ2	InterPro	422