ZFIN is now using GRCz12tu for Genomic Data

Gene

nrxn3a

ID

ZDB-GENE-070206-9

Name

neurexin 3a

Symbol

nrxn3a Nomenclature History

Previous Names

nrxn3aa
nrxn3ab
im:7144250
wu:fj54c11

Type

protein_coding_gene

Location

Chr: 17 Mapping Details/Browsers

Genome Assembly

GRCz12tu

Annotation Status

Current

Description

Predicted to enable neuroligin family protein binding activity and transmembrane signaling receptor activity. Predicted to be involved in several processes, including adult behavior; gephyrin clustering involved in postsynaptic density assembly; and learning. Predicted to be located in membrane. Predicted to be part of trans-synaptic protein complex. Predicted to be active in presynaptic active zone membrane. Is expressed in hair cell and lateral line. Human ortholog(s) of this gene implicated in alcohol dependence and nicotine dependence. Orthologous to human NRXN3 (neurexin 3).

Genome Resources

Note

nrxn3a has two isoforms, alpha (2 forms DQ641432 and DQ641433) and beta (DQ641434)

Comparative Information

Expression

All Expression Data

4 figures from 4 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

IMAGE:7144250 (1 image)

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With nrxn3a Human Ortholog

No data available

Associated With nrxn3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR000742	EGF-like domain
Domain	IPR001791	Laminin G domain
Domain	IPR003585	Neurexin/syndecan/glycophorin C
Domain	IPR027789	Syndecan/Neurexin domain
Family	IPR050372	Neurexin-related cell adhesion and synaptic protein
Homologous_superfamily	IPR013320	Concanavalin A-like lectin/glucanase domain superfamily

Domain Details Per Protein

Protein	Additional Resources	Length
UniProtKB:A0A8M9PKU0	InterPro	1464
UniProtKB:A0A8M9PEA6	InterPro	1681
UniProtKB:A0A8M9P901	InterPro	464
UniProtKB:A0A8M9PEB2	InterPro	1470
UniProtKB:A1XQY0	InterPro	672
UniProtKB:A0A8M9P8Z3	InterPro	1686
UniProtKB:A0A8M9P070	InterPro	1687
UniProtKB:A0A8M9PNT7	InterPro	1673
UniProtKB:A0A8M9P072	InterPro	1664
UniProtKB:A1XQX8	InterPro	1697
UniProtKB:A0A8M9PKT1	InterPro	1692
UniProtKB:A0A8M9P074	InterPro	1462
UniProtKB:A0A8M9P8Z6	InterPro	1473
UniProtKB:A0A8M9PKT6	InterPro	1672
UniProtKB:A0AB13AAE4	InterPro	1690
UniProtKB:A0AB32T3Q3	InterPro	1686
UniProtKB:A0AB32T3Q6	InterPro	1669
UniProtKB:A0AB32T508	InterPro	1487
UniProtKB:A0AB32T5M1	InterPro	1484
UniProtKB:A0AB32T643	InterPro	1569
UniProtKB:A0AB32T6G7	InterPro	1591
UniProtKB:A0AB32T7F7	InterPro	1465
UniProtKB:A0AB32T7L8	InterPro	461
UniProtKB:A0AB32T9B9	InterPro	1588
UniProtKB:A0AB32TAR3	InterPro	1695
UniProtKB:A0AB32TB23	InterPro	1566

Transcripts

Genome Browsers

NCBI Map Viewer

ZFIN

Type	Name	Annotation Method	Length (nt)	Analysis
aberrant processed transcript	nrxn3a-204 (1) Ensembl	Ensembl	2,987 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-201 (1) Ensembl	Ensembl	3,623 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-202 (1) Ensembl	Ensembl	2,099 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-203 (1) Ensembl	Ensembl	2,408 nt	Select Tool ZFIN BLAST
mRNA	nrxn3a-208 (1) Ensembl	Ensembl	4,008 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-004 (1) Ensembl	Ensembl	788 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-005 (1) Ensembl	Ensembl	776 nt	Select Tool ZFIN BLAST
ncRNA	nrxn3a-006 (1) Ensembl	Ensembl	437 nt	Select Tool ZFIN BLAST

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Genome Browsers

NCBI Map Viewer

ZFIN

Orthology

Comparative Orthology: Alliance
Gene Tree: Ensembl

Citations